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Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports
INTRODUCTION: Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown. CASE PRESENTATION: We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783063/ https://www.ncbi.nlm.nih.gov/pubmed/19946540 http://dx.doi.org/10.1186/1752-1947-3-123 |
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author | Gregoriou, Stamatis Chiolou, Zoe Stefanaki, Christina Zakopoulou, Niki Rigopoulos, Dimitrios Kontochristopoulos, George |
author_facet | Gregoriou, Stamatis Chiolou, Zoe Stefanaki, Christina Zakopoulou, Niki Rigopoulos, Dimitrios Kontochristopoulos, George |
author_sort | Gregoriou, Stamatis |
collection | PubMed |
description | INTRODUCTION: Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown. CASE PRESENTATION: We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile. CONCLUSION: Pityriasis rubra pillaris is currently classified as a keratinization disorder. The abnormal immunological profile reported in our patients along with the comorbidity of pityriasis rubra pilaris with autoimmune disorders reported in the literature poses the question of a possible pathogenetic role for the immune response in this disorder. |
format | Text |
id | pubmed-2783063 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27830632009-11-26 Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports Gregoriou, Stamatis Chiolou, Zoe Stefanaki, Christina Zakopoulou, Niki Rigopoulos, Dimitrios Kontochristopoulos, George J Med Case Reports Case report INTRODUCTION: Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown. CASE PRESENTATION: We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile. CONCLUSION: Pityriasis rubra pillaris is currently classified as a keratinization disorder. The abnormal immunological profile reported in our patients along with the comorbidity of pityriasis rubra pilaris with autoimmune disorders reported in the literature poses the question of a possible pathogenetic role for the immune response in this disorder. BioMed Central 2009-11-13 /pmc/articles/PMC2783063/ /pubmed/19946540 http://dx.doi.org/10.1186/1752-1947-3-123 Text en Copyright ©2009 Gregoriou et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case report Gregoriou, Stamatis Chiolou, Zoe Stefanaki, Christina Zakopoulou, Niki Rigopoulos, Dimitrios Kontochristopoulos, George Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title | Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title_full | Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title_fullStr | Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title_full_unstemmed | Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title_short | Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
title_sort | pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports |
topic | Case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783063/ https://www.ncbi.nlm.nih.gov/pubmed/19946540 http://dx.doi.org/10.1186/1752-1947-3-123 |
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