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Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report
INTRODUCTION: Myopia has become a big public health problem in certain parts of the world. Sight-threatening complications like choroidal neovascularisation membranes occur in up to 10% of pathological myopia, and natural history studies show a trend towards progressive visual loss. There are long-t...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783083/ https://www.ncbi.nlm.nih.gov/pubmed/19946560 http://dx.doi.org/10.1186/1752-1947-3-84 |
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author | Kumaran, Neruban Sim, Dawn A Tufail, Adnan |
author_facet | Kumaran, Neruban Sim, Dawn A Tufail, Adnan |
author_sort | Kumaran, Neruban |
collection | PubMed |
description | INTRODUCTION: Myopia has become a big public health problem in certain parts of the world. Sight-threatening complications like choroidal neovascularisation membranes occur in up to 10% of pathological myopia, and natural history studies show a trend towards progressive visual loss. There are long-term financial and quality-of-life implications in this group of patients, and treatment strategies should aim for long-term preservation of vision. CASE PRESENTATION: A 56-year-old Caucasian woman presented with a best-corrected visual acuity of 6/6-1 in her right eye and 6/24 in her left. Fundal examination revealed pathological myopia in both eyes and an elevated lesion associated with pre-retinal haemorrhage in the left macula. Ocular coherence tomography and fundus fluorescein angiogram confirmed a subfoveal classic choroidal neovascularisation membrane. The patient decided to proceed with intravitreal ranibizumab (0.5 mg) therapy. One month after treatment, best-corrected visual acuity improved to 6/12 in her left eye, with complete resolution subretinal fluid on ocular coherence tomography. After three months, best-corrected visual acuity further improved to 6/9, which was maintained up to 16 months post-treatment. CONCLUSION: We suggest intravitreal ranibizumab as an alternative treatment for long-term remission of myopic choroidal neovascular membrane. It also suggests that myopic choroidal neovascularisation membranes may require fewer treatments to achieve sustained remission. Furthermore, this could serve as a feasible long-term management option if used in conjunction with ocular coherence tomography. |
format | Text |
id | pubmed-2783083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27830832009-11-26 Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report Kumaran, Neruban Sim, Dawn A Tufail, Adnan J Med Case Reports Case report INTRODUCTION: Myopia has become a big public health problem in certain parts of the world. Sight-threatening complications like choroidal neovascularisation membranes occur in up to 10% of pathological myopia, and natural history studies show a trend towards progressive visual loss. There are long-term financial and quality-of-life implications in this group of patients, and treatment strategies should aim for long-term preservation of vision. CASE PRESENTATION: A 56-year-old Caucasian woman presented with a best-corrected visual acuity of 6/6-1 in her right eye and 6/24 in her left. Fundal examination revealed pathological myopia in both eyes and an elevated lesion associated with pre-retinal haemorrhage in the left macula. Ocular coherence tomography and fundus fluorescein angiogram confirmed a subfoveal classic choroidal neovascularisation membrane. The patient decided to proceed with intravitreal ranibizumab (0.5 mg) therapy. One month after treatment, best-corrected visual acuity improved to 6/12 in her left eye, with complete resolution subretinal fluid on ocular coherence tomography. After three months, best-corrected visual acuity further improved to 6/9, which was maintained up to 16 months post-treatment. CONCLUSION: We suggest intravitreal ranibizumab as an alternative treatment for long-term remission of myopic choroidal neovascular membrane. It also suggests that myopic choroidal neovascularisation membranes may require fewer treatments to achieve sustained remission. Furthermore, this could serve as a feasible long-term management option if used in conjunction with ocular coherence tomography. BioMed Central 2009-10-28 /pmc/articles/PMC2783083/ /pubmed/19946560 http://dx.doi.org/10.1186/1752-1947-3-84 Text en Copyright ©2009 Kumaran et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case report Kumaran, Neruban Sim, Dawn A Tufail, Adnan Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title | Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title_full | Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title_fullStr | Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title_full_unstemmed | Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title_short | Long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
title_sort | long-term remission of myopic choroidal neovascular membrane after treatment with ranibizumab: a case report |
topic | Case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783083/ https://www.ncbi.nlm.nih.gov/pubmed/19946560 http://dx.doi.org/10.1186/1752-1947-3-84 |
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