Disruption of mesolimbic regulation of prefrontal cholinergic transmission in an animal model of schizophrenia and normalization by chronic clozapine treatment

Abnormal mesolimbic control of cortical cholinergic activity has been hypothesized to contribute to the cognitive symptoms of schizophrenia. Stimulation of NMDA receptors in nucleus accumbens (NAC) increases acetylcholine (ACh) release in prefrontal cortex (PFC), an activation thought to contribute...

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Detalles Bibliográficos
Autores principales: Alexander, Kathleen S., Brooks, Julie M., Sarter, Martin, Bruno, John P.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783192/
https://www.ncbi.nlm.nih.gov/pubmed/19693002
http://dx.doi.org/10.1038/npp.2009.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783192/
https://www.ncbi.nlm.nih.gov/pubmed/19693002
http://dx.doi.org/10.1038/npp.2009.105

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