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Inhibition of the histone demethylase LSD1 blocks α-herpesvirus lytic replication and reactivation from latency
Reversible methylation of histone tails serve as either positive signals recognized by transcriptional assemblies or negative signals that result in repression 1–4. Invading viral pathogens that depend upon the host cell’s transcriptional apparatus are also subject to the regulatory impact of chroma...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783573/ https://www.ncbi.nlm.nih.gov/pubmed/19855399 http://dx.doi.org/10.1038/nm.2051 |