Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types

Short cell-type specific promoter sequences are important for targeted gene therapy and studies of brain circuitry. We report on the ability of short promoter sequences to drive fluorescent protein expression in specific types of mammalian cortical inhibitory neurons using adeno-associated virus (AA...

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Detalles Bibliográficos
Autores principales: Nathanson, Jason L., Jappelli, Roberto, Scheeff, Eric D., Manning, Gerard, Obata, Kunihiko, Brenner, Sydney, Callaway, Edward M.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783723/
https://www.ncbi.nlm.nih.gov/pubmed/19949461
http://dx.doi.org/10.3389/neuro.04.019.2009

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