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Synthesis and Combinational Antibacterial Study of 5″-Modified Neomycin

A library of 5″-modified neomycin derivatives were synthesized for an antibacterial structure-activity optimization strategy. Two leads exhibited prominent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Antibacterial activities we...

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Detalles Bibliográficos
Autores principales:	Zhang, Jianjun, Keller, Katherine, Takemoto, Jon Y., Bensaci, Mekki, Litke, Anthony, Czyryca, Przemyslaw Greg, Chang, Cheng-Wei Tom
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783947/ https://www.ncbi.nlm.nih.gov/pubmed/19629142 http://dx.doi.org/10.1038/ja.2009.66

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