Cargando…

TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway

Platelet-derived growth factor-BB (PDGF) has been reported to provide tropic support for neurons in the central nervous system. The protective role of PDGF on dopaminergic neurons, especially in the context of HIV-associated dementia (HAD), however, remains largely unknown. Herein we demonstrate tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Honghong, Peng, Fuwang, Fan, Yi, Zhu, Xuhui, Hu, Gang, Buch, Shilpa
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783976/
https://www.ncbi.nlm.nih.gov/pubmed/19680266
http://dx.doi.org/10.1038/cdd.2009.108