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A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression, including type I interferon production, by promoting host mRNA degradation and inhibiting host translation, in infected cells. We present evidence that nsp1 uses a novel, two-pronged strategy to inhibit host...
Autores principales: | Kamitani, Wataru, Huang, Cheng, Narayanan, Krishna, Lokugamage, Kumari G, Makino, Shinji |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784181/ https://www.ncbi.nlm.nih.gov/pubmed/19838190 http://dx.doi.org/10.1038/nsmb.1680 |
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