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Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss

Deafness is the most common sensory disorder in humans and the aetiology of genetic deafness is complex. Mouse mutants have been crucial in identifying genes involved in hearing. However, many deafness genes remain unidentified. Using N-ethyl N−nitrosourea (ENU) mutagenesis to generate new mouse mod...

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Detalles Bibliográficos
Autores principales:	Mackenzie, F E, Parker, A, Parkinson, N J, Oliver, P L, Brooker, D, Underhill, P, Lukashkina, V A, Lukashkin, A N, Holmes, C, Brown, S D M
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784214/ https://www.ncbi.nlm.nih.gov/pubmed/19737145 http://dx.doi.org/10.1111/j.1601-183X.2009.00514.x

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