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Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats

INTRODUCTION: Disturbed alveolar fibrin turnover is a cardinal feature of severe pneumonia. Clinical studies suggest that natural inhibitors of coagulation exert lung-protective effects via anticoagulant and possibly also anti-inflammatory pathways. Intravenous infusion of the natural anticoagulants...

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Detalles Bibliográficos
Autores principales:	Hofstra, Jorrit J, Cornet, Alexander D, de Rooy, Bart F, Vlaar, Alexander P, van der Poll, Tom, Levi, Marcel, Zaat, Sebastian AJ, Schultz, Marcus J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784363/ https://www.ncbi.nlm.nih.gov/pubmed/19740417 http://dx.doi.org/10.1186/cc8040

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