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Expression of complement system components during aging and amyloid deposition in APP transgenic mice

BACKGROUND: A causal role of the complement system in Alzheimer's disease pathogenesis has been postulated based on the identification of different activated components up to the membrane attack complex at amyloid plaques in brain. However, histological studies of amyloid plaque bearing APP tra...

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Detalles Bibliográficos
Autores principales: Reichwald, Julia, Danner, Simone, Wiederhold, Karl-Heinz, Staufenbiel, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784442/
https://www.ncbi.nlm.nih.gov/pubmed/19917141
http://dx.doi.org/10.1186/1742-2094-6-35