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Initial activation of EpCAM cleavage via cell-to-cell contact

BACKGROUND: Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is frequently over-expressed in simple epithelia, progenitors, embryonic and tissue stem cells, carcinoma and cancer-initiating cells. Besides functioning as a homophilic adhesion protein, EpCAM is an oncogeni...

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Detalles Bibliográficos
Autores principales:	Denzel, Sabine, Maetzel, Dorothea, Mack, Brigitte, Eggert, Carola, Bärr, Gabriele, Gires, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784796/ https://www.ncbi.nlm.nih.gov/pubmed/19925656 http://dx.doi.org/10.1186/1471-2407-9-402

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