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Structure of Signal-regulatory Protein α: A LINK TO ANTIGEN RECEPTOR EVOLUTION

Signal-regulatory protein α (SIRPα) is a myeloid membrane receptor that interacts with the membrane protein CD47, a marker of self. We have solved the structure of the complete extracellular portion of SIRPα, comprising three immunoglobulin superfamily domains, by x-ray crystallography to 2.5 Å reso...

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Detalles Bibliográficos
Autores principales:	Hatherley, Deborah, Graham, Stephen C., Harlos, Karl, Stuart, David I., Barclay, A. Neil
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785349/ https://www.ncbi.nlm.nih.gov/pubmed/19628875 http://dx.doi.org/10.1074/jbc.M109.017566

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