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Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome

BACKGROUND: Irritable bowel syndrome (IBS) is largely viewed as a stress-related disorder caused by aberrant brain-gut–immune communication and altered gastrointestinal (GI) homeostasis. Accumulating evidence demonstrates that stress modulates innate immune responses; however, very little is known o...

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Detalles Bibliográficos
Autores principales:	McKernan, Declan P., Nolan, Aoife, Brint, Elizabeth K., O'Mahony, Siobhain M., Hyland, Niall P., Cryan, John F., Dinan, Timothy G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785428/ https://www.ncbi.nlm.nih.gov/pubmed/20011045 http://dx.doi.org/10.1371/journal.pone.0008226

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