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Functional activation of proline-rich tyrosine kinase2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a representative systemic autoimmune disease characterized by activated T cells and polyclonally activated B cells that produce autoantibodies. Activation of autoreactive T and B cells plays a pivotal role in the pathogenesis of this disease. A role...

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Detalles Bibliográficos
Autores principales: Wang, Meiying, Sun, Hongsheng, Zhang, Wei, Zhang, Yuanchao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785759/
https://www.ncbi.nlm.nih.gov/pubmed/19919693
http://dx.doi.org/10.1186/1471-2474-10-141