iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

BACKGROUND: Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is translocated with an unknown mechanism onto the plasma membrane, where it trigg...

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Detalles Bibliográficos
Autores principales: De Boo, Sara, Kopecka, Joanna, Brusa, Davide, Gazzano, Elena, Matera, Lina, Ghigo, Dario, Bosia, Amalia, Riganti, Chiara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785770/
https://www.ncbi.nlm.nih.gov/pubmed/19925669
http://dx.doi.org/10.1186/1476-4598-8-108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785770/
https://www.ncbi.nlm.nih.gov/pubmed/19925669
http://dx.doi.org/10.1186/1476-4598-8-108

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