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iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
BACKGROUND: Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is translocated with an unknown mechanism onto the plasma membrane, where it trigg...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785770/ https://www.ncbi.nlm.nih.gov/pubmed/19925669 http://dx.doi.org/10.1186/1476-4598-8-108 |