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Osmolyte solutions and protein folding

In this brief review we discuss the evolution of recent thought regarding the role and mechanism of osmolytes with respect to protein stability. Osmolytes are naturally occurring intracellular compounds that change the protein folding landscape. Contributions from experiments are considered in the c...

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Detalles Bibliográficos
Autores principales: Hu, Char Y, Pettitt, B Montgomery, Roesgen, Joerg
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786071/
https://www.ncbi.nlm.nih.gov/pubmed/19960095
http://dx.doi.org/10.3410/B1-41
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author Hu, Char Y
Pettitt, B Montgomery
Roesgen, Joerg
author_facet Hu, Char Y
Pettitt, B Montgomery
Roesgen, Joerg
author_sort Hu, Char Y
collection PubMed
description In this brief review we discuss the evolution of recent thought regarding the role and mechanism of osmolytes with respect to protein stability. Osmolytes are naturally occurring intracellular compounds that change the protein folding landscape. Contributions from experiments are considered in the context of current theory and simulation results.
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spelling pubmed-27860712009-12-02 Osmolyte solutions and protein folding Hu, Char Y Pettitt, B Montgomery Roesgen, Joerg F1000 Biol Rep Review Article In this brief review we discuss the evolution of recent thought regarding the role and mechanism of osmolytes with respect to protein stability. Osmolytes are naturally occurring intracellular compounds that change the protein folding landscape. Contributions from experiments are considered in the context of current theory and simulation results. Biology Reports Ltd 2009-05-28 /pmc/articles/PMC2786071/ /pubmed/19960095 http://dx.doi.org/10.3410/B1-41 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Hu, Char Y
Pettitt, B Montgomery
Roesgen, Joerg
Osmolyte solutions and protein folding
title Osmolyte solutions and protein folding
title_full Osmolyte solutions and protein folding
title_fullStr Osmolyte solutions and protein folding
title_full_unstemmed Osmolyte solutions and protein folding
title_short Osmolyte solutions and protein folding
title_sort osmolyte solutions and protein folding
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786071/
https://www.ncbi.nlm.nih.gov/pubmed/19960095
http://dx.doi.org/10.3410/B1-41
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