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Presence of Autoimmune Antibody in Chikungunya Infection
Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and sw...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787058/ https://www.ncbi.nlm.nih.gov/pubmed/19997520 http://dx.doi.org/10.1155/2009/840183 |
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author | Maek-a-nantawat, Wirach Silachamroon, Udomsak |
author_facet | Maek-a-nantawat, Wirach Silachamroon, Udomsak |
author_sort | Maek-a-nantawat, Wirach |
collection | PubMed |
description | Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators. |
format | Text |
id | pubmed-2787058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-27870582009-12-08 Presence of Autoimmune Antibody in Chikungunya Infection Maek-a-nantawat, Wirach Silachamroon, Udomsak Case Rep Med Case Report Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators. Hindawi Publishing Corporation 2009 2009-11-25 /pmc/articles/PMC2787058/ /pubmed/19997520 http://dx.doi.org/10.1155/2009/840183 Text en Copyright © 2009 W. Maek-a-nantawat and U. Silachamroon. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Maek-a-nantawat, Wirach Silachamroon, Udomsak Presence of Autoimmune Antibody in Chikungunya Infection |
title | Presence of Autoimmune Antibody in Chikungunya Infection |
title_full | Presence of Autoimmune Antibody in Chikungunya Infection |
title_fullStr | Presence of Autoimmune Antibody in Chikungunya Infection |
title_full_unstemmed | Presence of Autoimmune Antibody in Chikungunya Infection |
title_short | Presence of Autoimmune Antibody in Chikungunya Infection |
title_sort | presence of autoimmune antibody in chikungunya infection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787058/ https://www.ncbi.nlm.nih.gov/pubmed/19997520 http://dx.doi.org/10.1155/2009/840183 |
work_keys_str_mv | AT maekanantawatwirach presenceofautoimmuneantibodyinchikungunyainfection AT silachamroonudomsak presenceofautoimmuneantibodyinchikungunyainfection |