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Presence of Autoimmune Antibody in Chikungunya Infection

Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and sw...

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Detalles Bibliográficos
Autores principales: Maek-a-nantawat, Wirach, Silachamroon, Udomsak
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787058/
https://www.ncbi.nlm.nih.gov/pubmed/19997520
http://dx.doi.org/10.1155/2009/840183
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author Maek-a-nantawat, Wirach
Silachamroon, Udomsak
author_facet Maek-a-nantawat, Wirach
Silachamroon, Udomsak
author_sort Maek-a-nantawat, Wirach
collection PubMed
description Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators.
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spelling pubmed-27870582009-12-08 Presence of Autoimmune Antibody in Chikungunya Infection Maek-a-nantawat, Wirach Silachamroon, Udomsak Case Rep Med Case Report Chikungunya infection has recently re-emerged as an important arthropod-borne disease in Thailand. Recently, Southern Thailand was identified as a potentially endemic area for the chikungunya virus. Here, we report a case of severe musculoskeletal complication, presenting with muscle weakness and swelling of the limbs. During the investigation to exclude autoimmune muscular inflammation, high titers of antinuclear antibody were detected. This is the report of autoimmunity detection associated with an arbovirus infection. The symptoms can mimic autoimmune polymyositis disease, and the condition requires close monitoring before deciding to embark upon prolonged specific treatment with immunomodulators. Hindawi Publishing Corporation 2009 2009-11-25 /pmc/articles/PMC2787058/ /pubmed/19997520 http://dx.doi.org/10.1155/2009/840183 Text en Copyright © 2009 W. Maek-a-nantawat and U. Silachamroon. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Maek-a-nantawat, Wirach
Silachamroon, Udomsak
Presence of Autoimmune Antibody in Chikungunya Infection
title Presence of Autoimmune Antibody in Chikungunya Infection
title_full Presence of Autoimmune Antibody in Chikungunya Infection
title_fullStr Presence of Autoimmune Antibody in Chikungunya Infection
title_full_unstemmed Presence of Autoimmune Antibody in Chikungunya Infection
title_short Presence of Autoimmune Antibody in Chikungunya Infection
title_sort presence of autoimmune antibody in chikungunya infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787058/
https://www.ncbi.nlm.nih.gov/pubmed/19997520
http://dx.doi.org/10.1155/2009/840183
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