Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro

INTRODUCTION: Little is known about factors that induce meniscus damage. Since joint inflammation appears to be a causative factor for meniscal destruction, we investigated the influence of tumor necrosis factor (TNFα) on glycosaminoglycan (GAG) release and aggrecan cleavage in an in vitro model. ME...

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Detalles Bibliográficos
Autores principales: Voigt, Henning, Lemke, Angelika K, Mentlein, Rolf, Schünke, Michael, Kurz, Bodo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787293/
https://www.ncbi.nlm.nih.gov/pubmed/19778432
http://dx.doi.org/10.1186/ar2813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787293/
https://www.ncbi.nlm.nih.gov/pubmed/19778432
http://dx.doi.org/10.1186/ar2813

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