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Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells
INTRODUCTION: Loss of intervertebral disc (IVD) matrix and ultimately disc height as a result of 'degeneration' has been implicated as a major cause of low back pain (LBP). The use of anabolic growth factors as therapies to regenerate IVD matrix, hence restoring disc height and thus revers...
Autores principales: | Le Maitre, Christine L, Freemont, Anthony J, Hoyland, Judith A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787300/ https://www.ncbi.nlm.nih.gov/pubmed/19754961 http://dx.doi.org/10.1186/ar2808 |
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