Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

BACKGROUND: Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate gene expression. Differential miRNA expression in cancer versus normal tissue i...

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Detalles Bibliográficos
Autores principales: Sarver, Aaron L, French, Amy J, Borralho, Pedro M, Thayanithy, Venugopal, Oberg, Ann L, Silverstein, Kevin AT, Morlan, Bruce W, Riska, Shaun M, Boardman, Lisa A, Cunningham, Julie M, Subramanian, Subbaya, Wang, Liang, Smyrk, Tom C, Rodrigues, Cecilia MP, Thibodeau, Stephen N, Steer, Clifford J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787532/
https://www.ncbi.nlm.nih.gov/pubmed/19922656
http://dx.doi.org/10.1186/1471-2407-9-401

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