The pathways of interoceptive awareness

A network of cortical brain regions including the insula and anterior cingulate cortex (ACC) has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found the insula and ACC are not critical for awareness of hear...

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Detalles Bibliográficos
Autores principales: Khalsa, Sahib S, Rudrauf, David, Feinstein, Justin S, Tranel, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787640/
https://www.ncbi.nlm.nih.gov/pubmed/19881506
http://dx.doi.org/10.1038/nn.2411
Descripción
Sumario:A network of cortical brain regions including the insula and anterior cingulate cortex (ACC) has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found the insula and ACC are not critical for awareness of heartbeat sensations. Rather, both somatosensory afferents from the skin and a network including the insula and ACC mediate it. Together these pathways enable the core human experience of the cardiovascular state of the body.

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