The pathways of interoceptive awareness

A network of cortical brain regions including the insula and anterior cingulate cortex (ACC) has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found the insula and ACC are not critical for awareness of hear...

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Autores principales: Khalsa, Sahib S, Rudrauf, David, Feinstein, Justin S, Tranel, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787640/
https://www.ncbi.nlm.nih.gov/pubmed/19881506
http://dx.doi.org/10.1038/nn.2411
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author Khalsa, Sahib S
Rudrauf, David
Feinstein, Justin S
Tranel, Daniel
author_facet Khalsa, Sahib S
Rudrauf, David
Feinstein, Justin S
Tranel, Daniel
author_sort Khalsa, Sahib S
collection PubMed
description A network of cortical brain regions including the insula and anterior cingulate cortex (ACC) has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found the insula and ACC are not critical for awareness of heartbeat sensations. Rather, both somatosensory afferents from the skin and a network including the insula and ACC mediate it. Together these pathways enable the core human experience of the cardiovascular state of the body.
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spelling pubmed-27876402010-06-01 The pathways of interoceptive awareness Khalsa, Sahib S Rudrauf, David Feinstein, Justin S Tranel, Daniel Nat Neurosci Article A network of cortical brain regions including the insula and anterior cingulate cortex (ACC) has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found the insula and ACC are not critical for awareness of heartbeat sensations. Rather, both somatosensory afferents from the skin and a network including the insula and ACC mediate it. Together these pathways enable the core human experience of the cardiovascular state of the body. 2009-11-01 2009-12 /pmc/articles/PMC2787640/ /pubmed/19881506 http://dx.doi.org/10.1038/nn.2411 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Khalsa, Sahib S
Rudrauf, David
Feinstein, Justin S
Tranel, Daniel
The pathways of interoceptive awareness
title The pathways of interoceptive awareness
title_full The pathways of interoceptive awareness
title_fullStr The pathways of interoceptive awareness
title_full_unstemmed The pathways of interoceptive awareness
title_short The pathways of interoceptive awareness
title_sort pathways of interoceptive awareness
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787640/
https://www.ncbi.nlm.nih.gov/pubmed/19881506
http://dx.doi.org/10.1038/nn.2411
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