RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans

BACKGROUND: The strong familiality of living to extreme ages suggests that human longevity is genetically regulated. The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. There are likely many more genetic modif...

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Detalles Bibliográficos
Autores principales: Sebastiani, Paola, Montano, Monty, Puca, Annibale, Solovieff, Nadia, Kojima, Toshio, Wang, Meng C., Melista, Efthymia, Meltzer, Micah, Fischer, Sylvia E. J., Andersen, Stacy, Hartley, Stephen H., Sedgewick, Amanda, Arai, Yasumichi, Bergman, Aviv, Barzilai, Nir, Terry, Dellara F., Riva, Alberto, Anselmi, Chiara Viviani, Malovini, Alberto, Kitamoto, Aya, Sawabe, Motoji, Arai, Tomio, Gondo, Yasuyuki, Steinberg, Martin H., Hirose, Nobuyoshi, Atzmon, Gil, Ruvkun, Gary, Baldwin, Clinton T., Perls, Thomas T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788130/
https://www.ncbi.nlm.nih.gov/pubmed/20011587
http://dx.doi.org/10.1371/journal.pone.0008210

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