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The Acrylamide (S)-2 As a Positive and Negative Modulator of Kv7 Channels Expressed in Xenopus laevis Oocytes

BACKGROUND: Activation of voltage-gated potassium channels of the Kv7 (KCNQ) family reduces cellular excitability. These channels are therefore attractive targets for treatment of diseases characterized by hyperexcitability, such as epilepsy, migraine and neuropathic pain. Retigabine, which opens Kv...

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Detalles Bibliográficos
Autores principales:	Blom, Sigrid Marie, Schmitt, Nicole, Jensen, Henrik Sindal
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788219/ https://www.ncbi.nlm.nih.gov/pubmed/20011514 http://dx.doi.org/10.1371/journal.pone.0008251

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