Cargando…
Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes
This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the...
Autores principales: | Hannum, Gregory, Srivas, Rohith, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J., Karp, Richard M., Ideker, Trey |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788232/ https://www.ncbi.nlm.nih.gov/pubmed/20041197 http://dx.doi.org/10.1371/journal.pgen.1000782 |
Ejemplares similares
-
Improved functional overview of protein complexes using inferred epistatic relationships
por: Ryan, Colm, et al.
Publicado: (2011) -
Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data
por: Bandyopadhyay, Sourav, et al.
Publicado: (2008) -
Differential network biology
por: Ideker, Trey, et al.
Publicado: (2012) -
A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae
por: Ming Sun, Su, et al.
Publicado: (2020) -
Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems
por: Yu, Michael Ku, et al.
Publicado: (2016)