Cargando…
Angiotensin I-Converting Enzyme Mutation (Trp1197Stop) Causes a Dramatic Increase in Blood ACE
BACKGROUND: Angiotensin-converting enzyme (ACE) metabolizes many peptides and plays a key role in blood pressure regulation and vascular remodeling. Elevated ACE levels may be associated with an increased risk for different cardiovascular or respiratory diseases, including asthma. Previously, a mole...
Autores principales: | Nesterovitch, Andrew B., Hogarth, Kyle D., Adarichev, Vyacheslav A., Vinokour, Elena I., Schwartz, David E., Solway, Julian, Danilov, Sergei M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788243/ https://www.ncbi.nlm.nih.gov/pubmed/20011602 http://dx.doi.org/10.1371/journal.pone.0008282 |
Ejemplares similares
-
An Angiotensin I-Converting Enzyme Mutation (Y465D) Causes a Dramatic Increase in Blood ACE via Accelerated ACE Shedding
por: Danilov, Sergei M., et al.
Publicado: (2011) -
Angiotensin I-Converting Enzyme Gln1069Arg Mutation Impairs Trafficking to the Cell Surface Resulting in Selective Denaturation of the C-Domain
por: Danilov, Sergei M., et al.
Publicado: (2010) -
A Novel Splice-Site Mutation in Angiotensin I-Converting Enzyme (ACE) Gene, c.3691+1G>A (IVS25+1G>A), Causes a Dramatic Increase in Circulating ACE through Deletion of the Transmembrane Anchor
por: Persu, Alexandre, et al.
Publicado: (2013) -
A Novel Angiotensin I-Converting Enzyme Mutation (S333W) Impairs N-Domain Enzymatic Cleavage of the Anti-Fibrotic Peptide, AcSDKP
por: Danilov, Sergei M., et al.
Publicado: (2014) -
Conformational Fingerprinting Using Monoclonal Antibodies (on the Example of Angiotensin I-Converting Enzyme-ACE)
por: Danilov, S. M.
Publicado: (2017)