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Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease
BACKGROUND: The fibroblast growth factor (FGF) axis is an important mitogenic stimulus in prostate carcinogenesis. We have previously reported that transcript level of human similar expression to FGF (hSef), a key regulator of this pathway, is downregulated in clinical prostate cancer. In this study...
Autores principales: | Darby, S, Murphy, T, Thomas, H, Robson, C N, Leung, H Y, Mathers, M E, Gnanapragasam, V J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788253/ https://www.ncbi.nlm.nih.gov/pubmed/19888221 http://dx.doi.org/10.1038/sj.bjc.6605379 |
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