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A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation

BACKGROUND: The fibroblast growth factors (FGFs) are key regulators of embryonic development, tissue homeostasis and tumour angiogenesis. Binding of FGFs to their receptor(s) results in activation of several intracellular signalling cascades including phosphoinositide 3-kinase (PI3K) and phospholipa...

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Detalles Bibliográficos
Autores principales: Maffucci, Tania, Raimondi, Claudio, Abu-Hayyeh, Shadi, Dominguez, Veronica, Sala, Gianluca, Zachary, Ian, Falasca, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788267/
https://www.ncbi.nlm.nih.gov/pubmed/20011604
http://dx.doi.org/10.1371/journal.pone.0008285