Cargando…

A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation

BACKGROUND: The fibroblast growth factors (FGFs) are key regulators of embryonic development, tissue homeostasis and tumour angiogenesis. Binding of FGFs to their receptor(s) results in activation of several intracellular signalling cascades including phosphoinositide 3-kinase (PI3K) and phospholipa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maffucci, Tania, Raimondi, Claudio, Abu-Hayyeh, Shadi, Dominguez, Veronica, Sala, Gianluca, Zachary, Ian, Falasca, Marco
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788267/ https://www.ncbi.nlm.nih.gov/pubmed/20011604 http://dx.doi.org/10.1371/journal.pone.0008285

Ejemplares similares

Inositol Polyphosphate-Based Compounds as Inhibitors of Phosphoinositide 3-Kinase-Dependent Signaling
por: Maffucci, Tania, et al.
Publicado: (2020)

Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion
por: Mavrommati, Ioanna, et al.
Publicado: (2016)

Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells
por: Dominguez, Veronica, et al.
Publicado: (2011)

Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer
por: Emmanouilidi, Aikaterini, et al.
Publicado: (2019)

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
por: Maffucci, Tania, et al.
Publicado: (2005)

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
por: Tibolla, Gianpaolo, et al.
Publicado: (2013)

Phosphoinositide 3-kinase class II beta is a novel target in breast cancer therapy
por: Abbott, J, et al.
Publicado: (2010)

A novel and selective PDK1 inhibitor reduces breast cancer cell invasion and tumour growth
por: Raimondi, C, et al.
Publicado: (2010)

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts
por: Falasca, Marco, et al.
Publicado: (2014)

Signalling Properties of Inositol Polyphosphates
por: Maffucci, Tania, et al.
Publicado: (2020)

Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas
por: Janus, Joanna M., et al.
Publicado: (2017)

Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes
por: Sciorra, Vicki A., et al.
Publicado: (2002)

Expression of Phosphoinositide-Specific Phospholipase C Isoforms in Native Endothelial Cells
por: Béziau, Delphine M., et al.
Publicado: (2015)

Phosphoinositide-Dependent Signaling in Cancer: A Focus on Phospholipase C Isozymes
por: Owusu Obeng, Eric, et al.
Publicado: (2020)

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression
por: Chikh, Anissa, et al.
Publicado: (2016)

Arabidopsis AtPLC2 Is a Primary Phosphoinositide-Specific Phospholipase C in Phosphoinositide Metabolism and the Endoplasmic Reticulum Stress Response
por: Kanehara, Kazue, et al.
Publicado: (2015)

Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation
por: Burda, Paul-Christian, et al.
Publicado: (2023)

Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth
por: Cisse, Ouma, et al.
Publicado: (2019)

Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides
por: Haugh, Jason M., et al.
Publicado: (2000)

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
por: Fyffe, Chanse, et al.
Publicado: (2013)

Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation
por: Raabe, Andreas C, et al.
Publicado: (2011)

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion
por: Raimondi, Claudio, et al.
Publicado: (2016)

Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor
Publicado: (1991)

Chromatin-modifying agents convert fibroblasts to OCT4+ and VEGFR-2+ capillary tube-forming cells
por: Wary, Anita, et al.
Publicado: (2017)

Capillary Effect Enhancement in a Plastic Capillary Tube by Nanostructured Surface
por: Kurihara, Kazuma, et al.
Publicado: (2021)

Observations on the Use of Capillary Tubes in Vaccination
por: Husband, William
Publicado: (1851)

Expression Analysis of a Stress-Related Phosphoinositide-Specific Phospholipase C Gene in Wheat (Triticum aestivum L.)
por: Zhang, Ke, et al.
Publicado: (2014)

Disruption of Phosphoinositide-Specific Phospholipases Cγ1 Contributes to Extracellular Matrix Synthesis of Human Osteoarthritis Chondrocytes
por: Zeng, Guoqing, et al.
Publicado: (2014)

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome
por: Lelièvre, Hélène, et al.
Publicado: (2008)

The Arabidopsis DREB2 genetic pathway is constitutively repressed by basal phosphoinositide-dependent phospholipase C coupled to diacylglycerol kinase
por: Djafi, Nabila, et al.
Publicado: (2013)

Salicylic acid modulates levels of phosphoinositide dependent-phospholipase C substrates and products to remodel the Arabidopsis suspension cell transcriptome
por: Ruelland, Eric, et al.
Publicado: (2014)

Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells
por: Dai, Lianzhi, et al.
Publicado: (2017)

Safety evaluation of the food enzyme phosphoinositide phospholipase C from the genetically modified Bacillus licheniformis strain NZYM‐DI
por: Lambré, Claude, et al.
Publicado: (2022)

Corrigendum: Salicylic acid modulates levels of phosphoinositide dependent-phospholipase C substrates and products to remodel the Arabidopsis suspension cell transcriptome
por: Ruelland, Eric, et al.
Publicado: (2016)

U-73122 reduces the cell growth in cultured MG-63 ostesarcoma cell line involving Phosphoinositide-specific Phospholipases C
por: Lo Vasco, Vincenza Rita, et al.
Publicado: (2016)

An X-Domain Phosphoinositide Phospholipase C (PI-PLC-like) of Trypanosoma brucei Has a Surface Localization and Is Essential for Proliferation
por: Negrão, Núria W., et al.
Publicado: (2023)

Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease
por: Ando, Kunie, et al.
Publicado: (2021)

Adverse health effects of recruiting child soldiers
por: Abu-Hayyeh, Reem, et al.
Publicado: (2019)

Growth and Viability of Cutaneous Squamous Cell Carcinoma Cell Lines Display Different Sensitivities to Isoform-Specific Phosphoinositide 3-Kinase Inhibitors
por: Mannella, Viviana, et al.
Publicado: (2021)

Phosphoinositides and phagocytosis
por: Gillooly, David J., et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_1ot5b8j96dkfueeoup554kghki