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A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons
BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) displays pleiotropic activities, both dependent and independent of its inhibitory activity on matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMP-1 is strongly upregulated in reactive astrocytes and cortical neuron...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788270/ https://www.ncbi.nlm.nih.gov/pubmed/20011518 http://dx.doi.org/10.1371/journal.pone.0008289 |