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A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons

BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) displays pleiotropic activities, both dependent and independent of its inhibitory activity on matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMP-1 is strongly upregulated in reactive astrocytes and cortical neuron...

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Detalles Bibliográficos
Autores principales: Ould-yahoui, Adlane, Tremblay, Evelyne, Sbai, Oualid, Ferhat, Lotfi, Bernard, Anne, Charrat, Eliane, Gueye, Yatma, Lim, Ngee Han, Brew, Keith, Risso, Jean-Jacques, Dive, Vincent, Khrestchatisky, Michel, Rivera, Santiago
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788270/
https://www.ncbi.nlm.nih.gov/pubmed/20011518
http://dx.doi.org/10.1371/journal.pone.0008289