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Protein C Inhibitor—A Novel Antimicrobial Agent

Protein C inhibitor (PCI) is a heparin-binding serine proteinase inhibitor belonging to the family of serpin proteins. Here we describe that PCI exerts broad antimicrobial activity against bacterial pathogens. This ability is mediated by the interaction of PCI with lipid membranes, which subsequentl...

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Detalles Bibliográficos
Autores principales:	Malmström, Erik, Mörgelin, Matthias, Malmsten, Martin, Johansson, Linda, Norrby-Teglund, Anna, Shannon, Oonagh, Schmidtchen, Artur, Meijers, Joost C. M., Herwald, Heiko
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788422/ https://www.ncbi.nlm.nih.gov/pubmed/20019810 http://dx.doi.org/10.1371/journal.ppat.1000698

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