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DISPARE: DIScriminative PAttern REfinement for Position Weight Matrices

BACKGROUND: The accurate determination of transcription factor binding affinities is an important problem in biology and key to understanding the gene regulation process. Position weight matrices are commonly used to represent the binding properties of transcription factor binding sites but suffer f...

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Detalles Bibliográficos
Autores principales: da Piedade, Isabelle, Tang, Man-Hung Eric, Elemento, Olivier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788558/
https://www.ncbi.nlm.nih.gov/pubmed/19941641
http://dx.doi.org/10.1186/1471-2105-10-388

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