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Nuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer

BACKGROUND: Y-box binding protein-1 (YB-1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus YB-1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translat...

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Detalles Bibliográficos
Autores principales: Dahl, Edgar, En-Nia, Abdelaziz, Wiesmann, Frank, Krings, Renate, Djudjaj, Sonja, Breuer, Elisabeth, Fuchs, Thomas, Wild, Peter J, Hartmann, Arndt, Dunn, Sandra E, Mertens, Peter R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788584/
https://www.ncbi.nlm.nih.gov/pubmed/19930682
http://dx.doi.org/10.1186/1471-2407-9-410