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Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo

Hematocrit (Hct) as an indicator of blood viscosity and mean arterial blood pressure (MAP) were assessed according to the season in adult participants of health screenings conducted throughout Kinshasa, Democratic Republic of Congo. Data was collected at the end of summer (April) and the end of wint...

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Autores principales: Hightower, C Makena, Hightower, Joyce D, Vázquez, Beatriz Y Salazar, Intaglietta, Marcos
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788592/
https://www.ncbi.nlm.nih.gov/pubmed/19997569
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author Hightower, C Makena
Hightower, Joyce D
Vázquez, Beatriz Y Salazar
Intaglietta, Marcos
author_facet Hightower, C Makena
Hightower, Joyce D
Vázquez, Beatriz Y Salazar
Intaglietta, Marcos
author_sort Hightower, C Makena
collection PubMed
description Hematocrit (Hct) as an indicator of blood viscosity and mean arterial blood pressure (MAP) were assessed according to the season in adult participants of health screenings conducted throughout Kinshasa, Democratic Republic of Congo. Data was collected at the end of summer (April) and the end of winter (August) and identified by gender. Male Hcts in August were significantly higher (P < 0.0001) than in April (48.3% ± 4.2% and 45.7% ± 2.3%, respectively) while male MAP (85.0 ± 8.4 mm Hg) was identical to that recorded in April (85.4 ± 7.7 mm Hg). August female Hcts (41.4% ± 3.1%) were statistically higher than those recorded in April (39.6% ± 1.9%, P = 0.001), MAP being 82.3 ± 7.3 vs 87.9 ± 6.6 mm Hg, respectively (P = 0.0001). Systolic and diastolic blood pressures, heart rate, body mass indices, ages, and personal and familial medical histories of the August and April groups were not significantly different. This study offers further support for the assertion that the relationship between blood viscosity and pressure of a healthy population shows that increased Hct, and therefore increased blood viscosity is associated with lowered MAP, and presumably peripheral vascular resistance.
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spelling pubmed-27885922009-12-07 Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo Hightower, C Makena Hightower, Joyce D Vázquez, Beatriz Y Salazar Intaglietta, Marcos Vasc Health Risk Manag Original Research Hematocrit (Hct) as an indicator of blood viscosity and mean arterial blood pressure (MAP) were assessed according to the season in adult participants of health screenings conducted throughout Kinshasa, Democratic Republic of Congo. Data was collected at the end of summer (April) and the end of winter (August) and identified by gender. Male Hcts in August were significantly higher (P < 0.0001) than in April (48.3% ± 4.2% and 45.7% ± 2.3%, respectively) while male MAP (85.0 ± 8.4 mm Hg) was identical to that recorded in April (85.4 ± 7.7 mm Hg). August female Hcts (41.4% ± 3.1%) were statistically higher than those recorded in April (39.6% ± 1.9%, P = 0.001), MAP being 82.3 ± 7.3 vs 87.9 ± 6.6 mm Hg, respectively (P = 0.0001). Systolic and diastolic blood pressures, heart rate, body mass indices, ages, and personal and familial medical histories of the August and April groups were not significantly different. This study offers further support for the assertion that the relationship between blood viscosity and pressure of a healthy population shows that increased Hct, and therefore increased blood viscosity is associated with lowered MAP, and presumably peripheral vascular resistance. Dove Medical Press 2009 2009-11-23 /pmc/articles/PMC2788592/ /pubmed/19997569 Text en © 2009 Hightower et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Hightower, C Makena
Hightower, Joyce D
Vázquez, Beatriz Y Salazar
Intaglietta, Marcos
Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title_full Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title_fullStr Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title_full_unstemmed Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title_short Seasonal hematocrit variation and health risks in the adult population of Kinshasa, Democratic Republic of Congo
title_sort seasonal hematocrit variation and health risks in the adult population of kinshasa, democratic republic of congo
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788592/
https://www.ncbi.nlm.nih.gov/pubmed/19997569
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