An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

Histone variant H2A.Z has a conserved role in genome stability, although it remains unclear how this is mediated. Here we demonstrate in fission yeast that the Swr1 ATPase inserts H2A.Z (Pht1) into chromatin and Kat5 acetyltransferase (Mst1) acetylates it. Deletion or unacetylatable mutation of Pht1...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Soo, Vanoosthuyse, Vincent, Fillingham, Jeffrey, Roguev, Assen, Watt, Stephen, Kislinger, Thomas, Treyer, Alex, Carpenter, Laura Rocco, Bennett, Christopher S., Emili, Andrew, Greenblatt, Jack F., Hardwick, Kevin G., Krogan, Nevan J., Bähler, Jürg, Keogh, Michael-Christopher
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788674/
https://www.ncbi.nlm.nih.gov/pubmed/19915592
http://dx.doi.org/10.1038/nsmb.1688

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