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Bi-Directional SIFT Predicts a Subset of Activating Mutations

Advancements in sequencing technologies have empowered recent efforts to identify polymorphisms and mutations on a global scale. The large number of variations and mutations found in these projects requires high-throughput tools to identify those that are most likely to have an impact on function. N...

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Detalles Bibliográficos
Autores principales: Lee, William, Zhang, Yan, Mukhyala, Kiran, Lazarus, Robert A., Zhang, Zemin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788704/
https://www.ncbi.nlm.nih.gov/pubmed/20011534
http://dx.doi.org/10.1371/journal.pone.0008311