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CRISPI: a CRISPR interactive database
Summary: The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788928/ https://www.ncbi.nlm.nih.gov/pubmed/19846435 http://dx.doi.org/10.1093/bioinformatics/btp586 |
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author | Rousseau, Christine Gonnet, Mathieu Le Romancer, Marc Nicolas, Jacques |
author_facet | Rousseau, Christine Gonnet, Mathieu Le Romancer, Marc Nicolas, Jacques |
author_sort | Rousseau, Christine |
collection | PubMed |
description | Summary: The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers. Availability: CRISPI free access at http://crispi.genouest.org Contact: croussea@irisa.fr; jnicolas@irisa.fr; |
format | Text |
id | pubmed-2788928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27889282009-12-07 CRISPI: a CRISPR interactive database Rousseau, Christine Gonnet, Mathieu Le Romancer, Marc Nicolas, Jacques Bioinformatics Applications Note Summary: The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers. Availability: CRISPI free access at http://crispi.genouest.org Contact: croussea@irisa.fr; jnicolas@irisa.fr; Oxford University Press 2009-12-15 2009-10-21 /pmc/articles/PMC2788928/ /pubmed/19846435 http://dx.doi.org/10.1093/bioinformatics/btp586 Text en http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Note Rousseau, Christine Gonnet, Mathieu Le Romancer, Marc Nicolas, Jacques CRISPI: a CRISPR interactive database |
title | CRISPI: a CRISPR interactive database |
title_full | CRISPI: a CRISPR interactive database |
title_fullStr | CRISPI: a CRISPR interactive database |
title_full_unstemmed | CRISPI: a CRISPR interactive database |
title_short | CRISPI: a CRISPR interactive database |
title_sort | crispi: a crispr interactive database |
topic | Applications Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788928/ https://www.ncbi.nlm.nih.gov/pubmed/19846435 http://dx.doi.org/10.1093/bioinformatics/btp586 |
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