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Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
Major histocompatibility complex (MHC) class II tetramers allow the direct visualization of antigen specific CD4+ T cells by flow cytometry. This method relies on the highly specific interaction between peptide loaded MHC and the corresponding T-cell receptor. While the affinity of a single MHC/pept...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789100/ https://www.ncbi.nlm.nih.gov/pubmed/19270641 http://dx.doi.org/10.3791/1167 |