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Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers

Major histocompatibility complex (MHC) class II tetramers allow the direct visualization of antigen specific CD4+ T cells by flow cytometry. This method relies on the highly specific interaction between peptide loaded MHC and the corresponding T-cell receptor. While the affinity of a single MHC/pept...

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Detalles Bibliográficos
Autores principales:	James, Eddie A., LaFond, Rebecca, Durinovic-Bello, Ivana, Kwok, William
Formato:	Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2009
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789100/ https://www.ncbi.nlm.nih.gov/pubmed/19270641 http://dx.doi.org/10.3791/1167

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