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Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B–ESAT6 fusion protein

A recombinant Salmonella enterica serovar Typhimurium (S. Typhimurium) vaccine strain was constructed that stably expressed the Mycobacterium tuberculosis fusion antigen Ag85B–ESAT6 from the chromosome. Live oral vaccination of mice with the Salmonella/Ag85B–ESAT6 strain generated a potent anti-Ag85...

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Detalles Bibliográficos
Autores principales:	Hall, Lindsay J., Clare, Simon, Pickard, Derek, Clark, Simon O., Kelly, Dominic L.F., Ghany, Moataz Abd El, Hale, Christine, Dietrich, Jes, Andersen, Peter, Marsh, Philip D., Dougan, Gordon
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier Science 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789253/ https://www.ncbi.nlm.nih.gov/pubmed/19755145 http://dx.doi.org/10.1016/j.vaccine.2009.09.007

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