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Rational Mutational Analysis of a Multidrug MFS Transporter CaMdr1p of Candida albicans by Employing a Membrane Environment Based Computational Approach

CaMdr1p is a multidrug MFS transporter of pathogenic Candida albicans. An over-expression of the gene encoding this protein is linked to clinically encountered azole resistance. In-depth knowledge of the structure and function of CaMdr1p is necessary for an effective design of modulators or inhibito...

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Detalles Bibliográficos
Autores principales:	Kapoor, Khyati, Rehan, Mohd, Kaushiki, Ajeeta, Pasrija, Ritu, Lynn, Andrew M., Prasad, Rajendra
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789324/ https://www.ncbi.nlm.nih.gov/pubmed/20041202 http://dx.doi.org/10.1371/journal.pcbi.1000624

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