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Voltage-Dependent Modulation of Cardiac Ryanodine Receptors (RyR2) by Protamine
It has been reported that protamine (>10 µg/ml) blocks single skeletal RyR1 channels and inhibits RyR1-mediated Ca(2+) release from sarcoplasmic reticulum microsomes. We extended these studies to cardiac RyR2 reconstituted into planar lipid bilayers. We found that protamine (0.02–20 µg/ml) added...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789381/ https://www.ncbi.nlm.nih.gov/pubmed/20016815 http://dx.doi.org/10.1371/journal.pone.0008315 |