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An Engineered Yeast Efficiently Secreting Penicillin

This study aimed at developing an alternative host for the production of penicillin (PEN). As yet, the industrial production of this β-lactam antibiotic is confined to the filamentous fungus Penicillium chrysogenum. As such, the yeast Hansenula polymorpha, a recognized producer of pharmaceuticals, r...

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Detalles Bibliográficos
Autores principales:	Gidijala, Loknath, Kiel, Jan A. K. W., Douma, Rutger D., Seifar, Reza M., van Gulik, Walter M., Bovenberg, Roel A. L., Veenhuis, Marten, van der Klei, Ida J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789386/ https://www.ncbi.nlm.nih.gov/pubmed/20016817 http://dx.doi.org/10.1371/journal.pone.0008317

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