Cargando…

Coordinated Regulation of SIV Replication and Immune Responses in the CNS

Central nervous system (CNS) invasion during acute-stage HIV-infection has been demonstrated in a small number of individuals, but there is no evidence of neurological impairment at this stage and virus infection in brain appears to be controlled until late-stage disease. Using our reproducible SIV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Witwer, Kenneth W., Gama, Lucio, Li, Ming, Bartizal, Christopher M., Queen, Suzanne E., Varrone, John J., Brice, Angela K., Graham, David R., Tarwater, Patrick M., Mankowski, Joseph L., Zink, M. Christine, Clements, Janice E.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790080/ https://www.ncbi.nlm.nih.gov/pubmed/20019816 http://dx.doi.org/10.1371/journal.pone.0008129

Ejemplares similares

SIV replication is directly downregulated by four antiviral miRNAs
por: Sisk, Jeanne M, et al.
Publicado: (2013)

Induction of Innate Immune Responses by SIV In Vivo and In Vitro: Differential Expression and Function of RIG-I and MDA5
por: Co, Juliene G., et al.
Publicado: (2011)

Natural Host Genetic Resistance to Lentiviral CNS Disease: A Neuroprotective MHC Class I Allele in SIV-Infected Macaques
por: Mankowski, Joseph L., et al.
Publicado: (2008)

Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity
por: Ravimohan, Shruthi, et al.
Publicado: (2012)

Correction: Early Emergence and Selection of a SIV-LTR C/EBP Site Variant in SIV-Infected Macaques That Increases Virus Infectivity
por: Ravimohan, Shruthi, et al.
Publicado: (2013)

Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain
por: Kelly, Kathleen M., et al.
Publicado: (2013)

CCR5 Inhibition Prevents Cardiac Dysfunction in the SIV/Macaque Model of HIV
por: Kelly, Kathleen M., et al.
Publicado: (2014)

Perturbations in the CD4(+)CD25(+ )regulatory T cell population of the GALT during acute SIV infection
por: Chase, Amanda J, et al.
Publicado: (2006)

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques
por: Hu, Haitao, et al.
Publicado: (2011)

Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system
por: Liu, Jonathan, et al.
Publicado: (2013)

RNA landscapes of brain tissue and brain tissue-derived extracellular vesicles in simian immunodeficiency virus (SIV) infection and SIV-related central nervous system pathology
por: Huang, Yiyao, et al.
Publicado: (2023)

Detection of Microbial Translocation in HIV and SIV Infection Using the Limulus Amebocyte Lysate Assay is Masked by Serum and Plasma
por: Balagopal, Ashwin, et al.
Publicado: (2012)

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques
por: Avalos, Claudia R., et al.
Publicado: (2016)

CD4 T cell Responses in the CNS during SIV infection
por: Elizaldi, Sonny R, et al.
Publicado: (2023)

SIV replication in human cells
por: Sakuma, Ryuta, et al.
Publicado: (2012)

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir
por: Avalos, Claudia R., et al.
Publicado: (2017)

Mechanisms of CNS Viral Seeding by HIV(+) CD14(+) CD16(+) Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders
por: Veenstra, Mike, et al.
Publicado: (2017)

miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction
por: Sisk, Jeanne M., et al.
Publicado: (2012)

Witwer, K.W.; et al. Correction: miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction. Viruses 2012, 4, 1844-1864
por: Sisk, Jeanne M., et al.
Publicado: (2013)

Infectious Virus Persists in CD4(+) T Cells and Macrophages in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques
por: Abreu, Celina M., et al.
Publicado: (2019)

Effect of Single Housing on Innate Immune Activation in Immunodeficiency Virus–Infected Pigtail Macaques (Macaca nemestrina) as a Model of Psychosocial Stress in Acute HIV Infection
por: Castell, Natalie, et al.
Publicado: (2022)

A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques
por: Matsuda, Kenta, et al.
Publicado: (2017)

Protection against highly pathogenic SIV by BCG-SIV recombinant priming and attenuated replicating vaccinia-SIV recombinant boosting
por: Zhang, X, et al.
Publicado: (2012)

Evaluation of a replication-competent VSV-SIV vaccine candidate
por: Jurgens, CK, et al.
Publicado: (2012)

Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2011)

Defining early SIV replication and dissemination dynamics following vaginal transmission
por: Deleage, Claire, et al.
Publicado: (2019)

Multiplexed Component Analysis to Identify Genes Contributing to the Immune Response during Acute SIV Infection
por: Hosseini, Iraj, et al.
Publicado: (2015)

Correction: Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication
por: Barsov, Eugene V., et al.
Publicado: (2018)

Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients
por: Witwer, Kenneth W, et al.
Publicado: (2012)

Quantitation of Gene Expression in Formaldehyde-Fixed and Fluorescence-Activated Sorted Cells
por: Russell, Julia N., et al.
Publicado: (2013)

Dual Role of Novel Ingenol Derivatives from Euphorbia tirucalli in HIV Replication: Inhibition of De Novo Infection and Activation of Viral LTR
por: Abreu, Celina M., et al.
Publicado: (2014)

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus
por: Reynolds, Matthew R., et al.
Publicado: (2008)

A conditionally replicating SIV variant that can be used to study the mechanism of protection conferred by live attenuated SIV vaccines
por: Das, Atze T, et al.
Publicado: (2011)

Myeloid and CD4 T Cells Comprise the Latent Reservoir in Antiretroviral Therapy-Suppressed SIVmac251-Infected Macaques
por: Abreu, Celina M., et al.
Publicado: (2019)

Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: Limited evidence for general uptake of dietary plant xenomiRs
por: Witwer, Kenneth W., et al.
Publicado: (2013)

SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load
por: Buchanan, Erin L., et al.
Publicado: (2016)

Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication
por: Haran, Kumudhini Preethi, et al.
Publicado: (2018)

miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease
por: Witwer, Kenneth W., et al.
Publicado: (2015)

Attenuation of Pathogenic Immune Responses during Infection with Human and Simian Immunodeficiency Virus (HIV/SIV) by the Tetracycline Derivative Minocycline
por: Drewes, Julia L., et al.
Publicado: (2014)

Regulation of CCL2 Expression by an Upstream TALE Homeodomain Protein-Binding Site That Synergizes with the Site Created by the A-2578G SNP
por: Page, Stephen H., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0sfnku6kjgn9l96m0ck06e4d1j