Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?

Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream a...

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Detalles Bibliográficos
Autor principal: Smalheiser, Neil R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790149/
https://www.ncbi.nlm.nih.gov/pubmed/20029619
http://dx.doi.org/10.1155/2009/383086
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author Smalheiser, Neil R.
author_facet Smalheiser, Neil R.
author_sort Smalheiser, Neil R.
collection PubMed
description Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.
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spelling pubmed-27901492009-12-22 Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles? Smalheiser, Neil R. Cardiovasc Psychiatry Neurol Hypothesis Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance. Hindawi Publishing Corporation 2009 2009-08-03 /pmc/articles/PMC2790149/ /pubmed/20029619 http://dx.doi.org/10.1155/2009/383086 Text en Copyright © 2009 Neil R. Smalheiser. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Hypothesis
Smalheiser, Neil R.
Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title_full Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title_fullStr Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title_full_unstemmed Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title_short Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
title_sort do neural cells communicate with endothelial cells via secretory exosomes and microvesicles?
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790149/
https://www.ncbi.nlm.nih.gov/pubmed/20029619
http://dx.doi.org/10.1155/2009/383086
work_keys_str_mv AT smalheiserneilr doneuralcellscommunicatewithendothelialcellsviasecretoryexosomesandmicrovesicles

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