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Collaborative annotation of genes and proteins between UniProtKB/Swiss-Prot and dictyBase

UniProtKB/Swiss-Prot, a curated protein database, and dictyBase, the Model Organism Database for Dictyostelium discoideum, have established a collaboration to improve data sharing. One of the major steps in this effort was the ‘Dicty annotation marathon’, a week-long exercise with 30 annotators aime...

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Detalles Bibliográficos
Autores principales: Gaudet, P., Lane, L., Fey, P., Bridge, A., Poux, S., Auchincloss, A., Axelsen, K., Braconi Quintaje, S., Boutet, E., Brown, P., Coudert, E., Datta, R.S., de Lima, W.C., de Oliveira Lima, T., Duvaud, S., Farriol-Mathis, N., Ferro Rojas, S., Feuermann, M., Gateau, A., Hinz, U., Hulo, C., James, J., Jimenez, S., Jungo, F., Keller, G., Lemercier, P., Lieberherr, D., Moinat, M., Nikolskaya, A., Pedruzzi, I., Rivoire, C., Roechert, B., Schneider, M., Stanley, E., Tognolli, M., Sjölander, K., Bougueleret, L., Chisholm, R.L., Bairoch, A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790310/
https://www.ncbi.nlm.nih.gov/pubmed/20157489
http://dx.doi.org/10.1093/database/bap016
Descripción
Sumario:UniProtKB/Swiss-Prot, a curated protein database, and dictyBase, the Model Organism Database for Dictyostelium discoideum, have established a collaboration to improve data sharing. One of the major steps in this effort was the ‘Dicty annotation marathon’, a week-long exercise with 30 annotators aimed at achieving a major increase in the number of D. discoideum proteins represented in UniProtKB/Swiss-Prot. The marathon led to the annotation of over 1000 D. discoideum proteins in UniProtKB/Swiss-Prot. Concomitantly, there were a large number of updates in dictyBase concerning gene symbols, protein names and gene models. This exercise demonstrates how UniProtKB/Swiss-Prot can work in very close cooperation with model organism databases and how the annotation of proteins can be accelerated through those collaborations.