Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src(@)

BACKGROUND: Epidermal growth factor receptor (EGFR) controls a wide range of cellular processes, and altered EGFR signaling contributes to human cancer. EGFR kinase domain mutants found in non-small cell lung cancer (NSCLC) are constitutively active, a trait critical for cell transformation through...

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Detalles Bibliográficos
Autores principales: Chung, Byung Min, Raja, Srikumar M, Clubb, Robert J, Tu, Chun, George, Manju, Band, Vimla, Band, Hamid
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790444/
https://www.ncbi.nlm.nih.gov/pubmed/19948031
http://dx.doi.org/10.1186/1471-2121-10-84

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