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Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms

BACKGROUND: Paraoxonase 1 (PON1) is an enzyme that detoxifies activated organophosphorus pesticides (OPs) and is also involved in oxidative stress pathways. OBJECTIVES: PON1 activity in newborns is lower than in adults, but the ontogeny of PON1 activity is poorly characterized in young children. We...

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Detalles Bibliográficos
Autores principales:	Huen, Karen, Harley, Kim, Brooks, Jordan, Hubbard, Alan, Bradman, Asa, Eskenazi, Brenda, Holland, Nina
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790521/ https://www.ncbi.nlm.nih.gov/pubmed/20019917 http://dx.doi.org/10.1289/ehp.0900870

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